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Obstetrics

Acid Peptic Disease in Pregnancy

Acid peptic disease is more common in pregnancy. Treat with lifestyle changes and pregnancy-safe agents.

ICD-10
—
Source
OPD handbook pp.48–49
Status
Draft

Not yet reviewed by a clinician. Check doses and brands against current national guidelines before use.

Symptoms

  • Burning chest pain aggravated by leaning forward
  • Excessive salivation

Diagnosis

  • Pregnant woman with reflux symptoms; examination unremarkable

Treatment

Step 1 of 4

1. Lifestyle modifications

  • Eat small amounts of food repeatedly
  • Increase fruit and vegetables; reduce tea and oily things
Step 2 of 4

2. PPI

  • Dexlansoprazole is the safest

Prescription

DexlansoprazoleProton pump inhibitor
Dose1+0 before breakfast
Brand Cap Delanzo DR 30 mg
Also sold as Dexo, Delanzo DR
Step 3 of 4

3. Antacids (safe)

Prescription

Dose2 tsf 2+2+2 after meals
Brand Syp Mucaine / Syp Dijex MP
Also sold as Dijex MP, Gaviscon Advance, Lagita Advance (as written), Mucaine
Safe in pregnancy
Step 4 of 4

4. Prokinetic (safe)

  • Metoclopramide is safe in pregnancy

Prescription

MetoclopramideProkinetic / antiemetic
Dose1+1+1
Brand Tab Maxolone 10 mg
Also sold as Maxolone, Maxolon, Metaclon, Metomide

Sample prescription from the book (patient details removed)

  • Pregnant woman, 26 y, burning chest pain aggravated by leaning forward and excessive salivation: Cap Delanzo DR 30 mg 1+0 before breakfast; Tab Maxolone 10 mg 1+1+1; Syp Mucaine 2+2+2 spoonfuls after meals; small frequent meals; more fruits and vegetables; reduce tea and oily things.
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