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Neurology

Epilepsy: Grand Mal (Note Sheet)

مرگی

First-line and add-on drugs for generalised (grand mal) epilepsy from a handwritten note sheet.

ICD-10
—
Source
OPD handbook p.214
Status
Draft

Not yet reviewed by a clinician. Check doses and brands against current national guidelines before use.

Symptoms

  • Generalised tonic-clonic seizures

Treatment

Step 1 of 2

1. First line

  • Tab Epival (sodium valproate) 250–500 mg, 1 tab BD

Prescription

Sodium valproateAntiepileptic
Dose250–500 mg, 1 tab BD
Brand Tab Epival
Step 2 of 2

2. If not controlled

  • Add Tab Lerace (levetiracetam) 250 mg, 1 tab increasing to 6 tabs daily (as read)
  • Add Tab Topamax (topiramate) 50 mg, 1 tab daily, and after 1 week 2 tabs daily

Prescription

LevetiracetamAntiepileptic
Dose1 tab, increasing up to 6 tabs daily (as read)
Brand Tab Lerace 250 mg
TopiramateAntiepileptic
Dose1 tab daily; after 1 week 2 tabs daily
Brand Tab Topamax 50 mg
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