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Paediatrics

Acute Watery Diarrhoea in Children

بچوں میں اسہال

A leading cause of death in under-5 children in Pakistan, but largely preventable with ORS and zinc. Antibiotics are rarely needed.

ICD-10
A09
Source
General reference written by the assistant (not from the OPD book); needs clinical review
Status
Draft

Not yet reviewed by a clinician. Check doses and brands against current national guidelines before use.

Symptoms

  • Three or more loose, watery stools a day
  • Vomiting
  • Thirst, sunken eyes, dry mouth
  • Fever (sometimes)
  • Reduced urine

Red flags Refer urgently if any are present

  • Lethargy, unconscious, floppy
  • Unable to drink or drinking poorly
  • Sunken eyes with skin pinch going back very slowly (severe dehydration)
  • Blood in stool (dysentery)
  • Diarrhoea lasting 14 days or more
  • Severe malnutrition or an infant under 2 months

Diagnosis

  • Clinical assessment of dehydration: general condition, eyes, thirst, skin pinch
  • Stool culture/microscopy only for dysentery, suspected cholera or outbreaks

Treatment

Step 1 of 5

Assess dehydration

WHO / IMCI classification: no dehydration, some dehydration, severe dehydration.

  • Look at general condition, eyes, thirst and skin pinch
  • Ask duration, blood in stool, vomiting, urine output
  • Weigh the child and look for malnutrition
Step 2 of 5

Plan A: no dehydration (home care)

  • Give extra fluids: ORS, soup, rice water, yoghurt drink (lassi) without sugar
  • Child under 2: 50–100 mL ORS after each loose stool; 2 to 10 years: 100–200 mL
  • Continue breastfeeding and normal feeding; do not stop food
  • Give zinc for 10–14 days
  • Return if not improving in 2 days, or if danger signs appear

Prescription

DoseAfter every loose stool, in small frequent sips
Brands WHO low-osmolarity ORS sachet Until diarrhoea stops
Free ORS is stocked at government facilities and distributed by Lady Health Workers. Many private ORS brands exist; check the sachet states the WHO low-osmolarity formula.
Caution: Mix with the exact volume of clean water stated on the sachet; Discard made-up solution after 24 hours
Zinc sulfateMicronutrient
DoseUnder 6 months 10 mg daily; 6 months or older 20 mg daily
Brands Zincat 10–14 days
Zinc dispersible tablets are part of the national diarrhoea management protocol.
Step 3 of 5

Plan B: some dehydration

  • Give ORS in the clinic over 4 hours: 75 mL/kg
  • Reassess after 4 hours and classify again
  • Show the caregiver how to give ORS; continue breastfeeding
  • If vomiting, wait 10 minutes and continue more slowly

Prescription

Dose75 mL/kg over 4 hours
Brands WHO low-osmolarity ORS sachet 4 hours
Free ORS is stocked at government facilities and distributed by Lady Health Workers. Many private ORS brands exist; check the sachet states the WHO low-osmolarity formula.
Caution: Mix with the exact volume of clean water stated on the sachet; Discard made-up solution after 24 hours
Zinc sulfateMicronutrient
DoseUnder 6 months 10 mg daily; 6 months or older 20 mg daily
Brands Zincat 10–14 days
Zinc dispersible tablets are part of the national diarrhoea management protocol.
Step 4 of 5

Plan C: severe dehydration

  • Start IV fluids at once: Ringer's lactate 100 mL/kg (30 mL/kg within 30 min for infants under 12 months, 1 h for older children, then 70 mL/kg over the next 5 h / 2.5 h)
  • Reassess frequently; start ORS as soon as the child can drink
  • Refer to hospital if IV therapy is unavailable, use nasogastric ORS en route (20 mL/kg/h)
  • Treat suspected cholera and dysentery with an appropriate antibiotic per local sensitivity

Prescription

Dose100 mL/kg in total (see split above)
Brands Generic / hospital supply 3–6 hours
Caution: Monitor for fluid overload, especially in dengue critical-phase recovery
AzithromycinMacrolide antibiotic
DoseChild 10–20 mg/kg single or 3-day course
Brands Zithromax, Azomax, Azitma, Arzomic, Zyto, Genthro Only for cholera or dysentery
Not for simple watery diarrhoea
Caution: QT prolongation; caution with other QT-prolonging drugs
Step 5 of 5

Recovery and nutrition

  • Give one extra meal a day for 2 weeks after diarrhoea stops
  • Check immunisation status: rotavirus and pneumococcal vaccines
  • Counsel on hand washing, clean water, and safe stool disposal

Prevention

  • Exclusive breastfeeding for 6 months
  • Rotavirus vaccine (in Pakistan's EPI schedule)
  • Hand washing with soap; safe water; sanitation
  • Vitamin A supplementation per EPI/nutrition guidance

Guideline sources

  • WHO Pocket book of hospital care for children
  • WHO/UNICEF ORS and zinc guidance
  • IMCI Pakistan
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