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Gastrointestinal

GERD (Gastro-Oesophageal Reflux Disease)

سینے کی جلن

Burning chest pain worse on leaning forward or after food, with excessive salivation and hiccups. Always be vigilant about chest pain and rule out a cardiac cause.

ICD-10
—
Source
OPD handbook pp.44–47, 50
Status
Draft

Not yet reviewed by a clinician. Check doses and brands against current national guidelines before use.

Symptoms

  • Burning chest pain, worse by leaning forward and by food intake
  • Excessive salivation
  • Hiccups

Red flags Refer urgently if any are present

  • Compressing chest pain
  • Cold peripheries
  • Known case of DM, HTN or IHD: rule out a cardiac cause

Diagnosis

  • Examination is unremarkable

Treatment

Step 1 of 4

1. Counselling

  • Cut down tea, oily and fried foods and bakery items
  • Take dinner two hours before sleeping
  • Do not lie on the bed straight after eating
  • Increase fruit and vegetables
  • Take curd (dahi) in the breakfast
  • Make a habit of eating salad
Step 2 of 4

2. Prokinetics

Prescription

MetoclopramideProkinetic / antiemetic
Dose10 mg TDS (1+1+1)
Brand Tab Maxolone 10 mg
Also sold as Maxolone, Maxolon, Metaclon, Metomide
MetoclopramideProkinetic / antiemetic
Dose2 tsf, 2+2+2 (morning, noon, evening)
Brand Syp Maxolone 5 mg/5 mL
Also sold as Maxolone, Maxolon, Metaclon, Metomide
DomperidoneProkinetic / antiemetic
Dose10 mg TDS (1+1+1), before meals
Brand Stomacol / Motilium
Also sold as Stomacol, Motilium, Peridone
Step 3 of 4

3. Antacids

  • Dose: 2 teaspoons TDS, half an hour after meals

Prescription

Dose2 tsf TDS after meals
Brand Syp Dijex MP / Gaviscon Advance / Lagita Advance
Also sold as Dijex MP, Gaviscon Advance, Lagita Advance (as written), Mucaine
Step 4 of 4

4. Proton pump inhibitors

  • In GERD the sachet form is preferred, e.g. Ruling sachet 40 mg 1+0, half an hour before breakfast
  • Dexlansoprazole is the safest in GERD and pregnancy

Prescription

OmeprazoleProton pump inhibitor
Dose40 mg OD
Brand Ruling / Risek / Teph / Sante
Also sold as Risek, Teph, Ruling, Ruling sachet, Omega
Ruling sachet 40 mg, 1+0 before breakfast
EsomeprazoleProton pump inhibitor
Dose40 mg OD
Brand Eskem / Novoteph / Esante
Also sold as Novoteph, Esante, Eskem, Eswin, Nexum, Esso, Exium
DexlansoprazoleProton pump inhibitor
Dose30 mg OD
Brand Dexo / Delanzo DR
Also sold as Dexo, Delanzo DR
Safest in GERD and pregnancy

Sample prescription from the book (patient details removed)

  • Male, 33 y, banker, burning chest pain on and off, increased with heavy meals; examination unremarkable: Ruling sachet 40 mg 1+0 before breakfast; Tab Stomacol 10 mg 1+1+1 before meals; Syp Dijex MP 2+2+2 after meals; avoid tea, oily and fried things; dinner two hours before sleeping; do not lie down straight after eating; light exercise; more fruit, vegetables and curd.
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